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What Is JWH 018? | JWH 018 (AM678, CAS Number: 209414-07-3)

JWH-018 (1-pentyl-3-(1-naphthoyl)indole, NA-PIMO[1] or AM-678)[2] is an analgesic compound from the naphthoylindole family that acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, with a slight preference for CB2 receptors.JWH 018 has become increasingly popular in recent years, but what is it exactly? JWH 018 is a compound that belongs to a group of compounds known as synthetic cannabinoids. It was first synthesized at Clemson University by Professor John W. Huffman, hence its name. The chemical formula of JWH-018 gave rise to its moniker. Buy JWH 018 powder

The “x” denotes that JWH-018 is a synthetic compound that was not created in nature. What does it serve? JWH-018 is regarded as a very potent hallucinogen and has an anesthetic effect on the human body. JWH-018 has been utilized over time to produce high-potency synthetic cannabis products that are offered for sale for use on the street.

JWH-018 is frequently utilized as a precursor to make designer cannabis products with increased THC and other active ingredients. This compound produces many of the same effects as THC but without the mind-altering high that comes along with it. where to buy JWH 018 in stores. Are there any side effects? JWH-018 is a powerful synthetic cannabinoid that’s far more potent than THC. Why Buy Research Chemicals Online?

A collection of synthetic cannabinoids known as the JWH series is named for John W. Huffman, who created them initially. Since all of these substances’ homologs are very closely related to one another, their actions are comparable and predictable. They are all complete agonists of the cannabinoid receptors, with JWH-018 being the strongest one in the group. Dr. Huffman created this drug in 1993, and its full effects weren’t known until 1994.


JWH-018, also known as naphthalen-1-yl-(1-pentylindol-3-yl)methanone, is a synthetic indole cannabinoid. Other cannabinoids including PB-22, 5F-PB-22, JWH-018, and AM2201 also share this indole core. A pentyl chain is replaced for JWH-018 at R1. Additionally, a carbonyl group substitutes the indole core at R3 and is linked to a napthalene moiety. Two fused benzene rings make up the bicyclic structure of napthalene. JWH-018 falls under the ketone category because of its carbonyl bridge. JWH-018 is a THJ-018 homologue in which an indole base is used in place of the core indazole structure.


JWH-018 has a reported binding affinity of 9.00 5.00 nM at CB1 and 2.94 2.65 nM at CB2, making it a complete agonist of both the CB1 and CB2 cannabinoid receptors. [6] The function of these interactions and how they lead to the cannabis high experience, however, are still poorly understood.

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How Does It Appear?

JWH 018 mimics THC in appearance. It does not have any psychedelic or hallucinogenic properties and is only marginally more potent than THC. The liquid spray is red and has a burning grass-like scent. The only form of JWH-018 that can be bought online is a powder that is white and has a sage-like scent. Your hands will be stained a faint shade of green, and

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