What is JWH-018? | JWH 018 for sale | Everything you need to know about JWH-018
What is JWH-018? JWH 018 powder is a synthetic cannabinoid. An organic chemist named John W. Huffman first made it in 2008. It gained popularity in 2009. German chemists found it then. It was a chemical in the popular synthetic cannabis blend Spice. Cannabinoid JWH 018 for sale
What is Jwh-018 synthetic cannabinoid?
JWH-018 is a synthetic cannabinoid whose chemical structure is based on that of both of the other two major cannabinoids used as precursors in making synthetic cannabinoid products. JWH-018 is slightly less potent than JWH-073. JWH-018 spray may have effects similar to those of other hallucinogenic synthetic cannabinoids and an onset of action that is similar to that of JWH-018.
JWH 018 is most often sold as a pill or liquid that is inserted into an inhaler.
What is JWH-018?
Property | Details |
---|---|
Common Names | K2, Spice, Black Mamba, Brazilian Beet, Euphoria, BPAL |
Formal Name | 1-naphthalene(1-pentyl-1H-indol-3-yl)-methanone |
Routes of Administration | Smoked, Oral |
Legal Status | AU: S9 (Prohibited substance), CA: Schedule II, DE: Anlage II (Authorized trade only, not prescriptible), UK: Class B, US: Schedule I |
IUPAC Name | naphthalene-1-yl(1-pentyl-1H-indol-3-yl)methanone |
CAS Number | 209414-07-3 |
PubChem CID | 10382701 |
ChemSpider | 8558143 |
UNII | G391998J57 |
ChEMBL | ChEMBL561013 |
Formula | C24H23NO |
Molar Mass | 341.454 g·mol−1 |
Solubility in Water | Hydrophobic, n/a mg/mL (20 °C) |
Purity | ≥98% |
SMILES | CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12 |
InChI Code | InChI=1S/C24H23NO/c1-2-3-8-16-25-17-22(20-13-6-7-15-23(20)25)24(26)21-14-9-11-18-10-4-5-12-19(18)21/h4-7,9-15,17H,2-3,8,16H2,1H3 |
InChI Key | JDNLPKCAXICMBW-UHFFFAOYSA-N |
Effects of JWH-018
JWH-018 can produce effects similar to THC but is often much more potent. The effects can include both desired and adverse reactions.
Effect | Description |
---|---|
Euphoria | Feelings of happiness and relaxation |
Altered Perception | Changes in sight, sound, and time perception |
Anxiety | Increased feelings of anxiety and panic |
Paranoia | Intense paranoia and suspicious thoughts |
Seizures | Risk of seizures, especially at high doses |
Psychosis | Can trigger psychotic episodes |
Risks and Dangers
Using JWH-018 comes with significant risks due to its potency and potential side effects.
Risk | Details |
---|---|
Addiction | Potential for psychological dependence |
Withdrawal | Severe withdrawal symptoms compared to cannabis |
Cardiovascular Issues | May cause heart problems, though not fully understood |
Mental Health | Can exacerbate existing mental health issues |
Where is JWH 018 found?
Street names for JWH 018
Chemicals such as Jwh-018, commonly referred to as “fake pot,” can be packaged under various names.
JWH-018 is sold as JWH-018 SPARY.
- K2,
- Spice,
- Black Mamba,
- Brazilian Beet,
- Euphoria,
- and BPAL.
-
Jawa
How to smoke JWH-018 powder
To smoke JWH-018 powder, you will first need to heat it to a liquid form. Once it is in liquid form, you can then use a syringe to inject it into a cigarette or vape cartridge. You can then smoke the cigarette or vape the cartridge as you would any other nicotine product.
Note that JWH-018 is a synthetic cannabinoid, so it will produce the same effects as other synthetic cannabinoids, such as Spice or K2. These effects can include relaxation, euphoria, and altered perception. JWH-018 is also reportedly more potent than other synthetic cannabinoids, so it is important to start with a low dose and increase it gradually if you are new to this drug.
Legal Status of JWH-018
The legal status of JWH-018 varies by country and has changed over time due to health concerns.
Country | Status |
---|---|
United States | Schedule I Controlled Substance |
United Kingdom | Class B Drug |
Australia | Schedule 9 Prohibited Substance |
Canada | Schedule II: Controlled Substance |
Germany | Controlled under the Narcotics Act |
Detection in Biological Fluids
JWH-018 can be detected in urine and blood, though specialized tests are required.
Test Type | Description |
---|---|
Urine Test | Detects parent drug and metabolites |
Blood Test | Measures concentrations in the blood |
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JWH-018 is a powerful synthetic cannabinoid that can produce intense effects. While it was initially created for research, its use in recreational products has led to significant health concerns and legal restrictions. Understanding its properties and risks is crucial for informed use and safety.
Summary Table
Aspect | Details |
---|---|
Chemical Name | Naphthalen-1-yl(1-pentyl-1H-indol-3-yl)methanone |
Effects | Euphoria, altered perception, anxiety, seizures |
Risks | Addiction, withdrawal, cardiovascular issues, psychosis |
Legal Status | It is illegal in many countries |
Detection | Urine and blood tests |
By understanding JWH-018, you can better appreciate the complexities and dangers of synthetic cannabinoids. Always stay informed and prioritize safety when dealing with such substances.
What is JWH-018, and what are its street names?
JWH-018, chemically known as 1-pentyl-3-(1-naphthoyl)indole, is a synthetic cannabinoid designed to mimic THC, the psychoactive compound in cannabis. Marketed under names like “Spice” or “K2,” it’s often sold as “herbal incense” but packs a far more dangerous punch. Unlike natural cannabis, JWH-018 binds aggressively to the brain’s cannabinoid receptors, leading to unpredictable and severe side effects .
What does “JWH” stand for?
The abbreviation JWH refers to John W. Huffman, the organic chemist at Clemson University who first synthesized this compound in the 1990s while researching pain management therapies. Ironically, his work has been co-opted to create illicSpice.s like Spice.
What are the acute side effects of JWH-018?
JWH-018’s potency as a full agonist at CB1 and CB2 receptors leads to intense physiological reactions:
- Cardiovascular strain: Rapid heart rate, hypertension, or even life-threatening bradycardia
- Neurological chaos: paranoia, hallucinations, and seizures .
- Respiratory issues: labored breathing and tachypnea .
Animal studies reveal that even low doses can disrupt heart rhythms, with antidotes like atropine only partially reversing these effects.
How does JWH-018 appear on a drug screen?
Standard THC tests often miss JWH-018. Instead, specialized LC-MS/MS screenings are required to detect its metabolites, such as hydroxylated compounds in urine. A 2010 study identified monohydroxylated metabolites as the primary markers, with concentrations ranging from 6–50 μg/L in users 7 Elite athletes are particularly scrutinized under World Anti-Doping Agency protocols due to their performance-altering risks .
What is JWH-073, and where is it found?
JWH-073, a structural analog of JWH-018, is another synthetic cannabinoid often mixed into products like “Forest Humus“ or post-ban Spice blends. Like JWH-018, it’s a full agonist at CB1 receptors but with slightly lower potency. After Germany banned JWH-018 in 2009, manufacturers substituted JWH-073 to skirt regulations.
How long do JWH-018’s effects last?
When inhaled, JWH-018 has a median half-life of 1.69 hours, but its metabolites linger for days. Hydroxylated compounds, particularly those glucuronide-conjugated, prolong detection windows in urine tests 67. Chronic use can lead to cumulative toxicity, with serum concentrations as low as 1–10 μg/L linked to fatal overdoses.
What are the long-term risks?
Repeated use rewires the brain, especially in adolescents. Studies in mice show:
- Cognitive decline: impaired memory and sensory gating, akin to schizophrenia
- Psychosis risk: microglial activation in the prefrontal cortex, reducing parvalbumin neurons critical for neural stability
- Dependency: withdrawal symptoms surpass those of cannabis, including severe anxiety and agitation .
Is JWH-018 legal?
Globally, over 30 countries have banned JWH-018, including the U.S., EU nations, and Australia. However, manufacturers exploit legal loopholes by tweaking its chemical structure (e.g., shortening the alkyl chain) to create new, unregulated variants 611.
Country | Ban Date | Legal Status Notes |
---|---|---|
United States | March 2011 | Schedule I controlled substance |
Germany | January 2009 | BtMG Anlage II |
Australia | September 2011 | Schedule 9 prohibited |
Can JWH-018 cause death?
Yes. Case reports link JWH-018 to organ failure and cardiac arrest, even in young, healthy individuals. A 2011 fatality in South Carolina was attributed to “drug toxicity and organ failure” from JWH-018 use
What should you do if someone overdoses?
No FDA-approved antidote exists. Emergency protocols focus on managing symptoms:
- Benzodiazepines for seizures.
- Beta-blockers for heart rate stabilization .
An immediate medical intervention is critical.
Final Takeaways
JWH-018 isn’t “safe high”—it’s a chemical gamble with irreversible consequences. From cardiac crises to lasting brain damage, its risks are stark. Stay informed, avoid synthetic blends, and seek help for dependency.
CTA: Need help or more info? Reach out to addiction support networks like SAMHSA or consult a healthcare provider.
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