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What is methoxetamine?

Methoxetamine (MXE) is a dissociative drug, which means it makes people feel divided or detached from their bodies or physical surroundings. Dissociatives, like psychedelics, can create hallucinations as well as other alterations in thoughts, emotions, and consciousness. MXE may also be known as M-ket, Kmax, and Mexxy. methoxetamine effects are similar to other dissociatives.

MXE is a New Psychoactive Substance as well (NPS). NPSs are a class of medications that have been created to imitate the effects of currently illicit substances. MXE, for example, seeks to mimic the effects of ketamine and has been marketed and sold online as a legal substitute. NPSs are, however, prohibited in some states and territories.

MXE is typically sold as a white, off-white, beige, or yellow powder, although it is also available in capsule and liquid form. It is frequently labeled “Not for Human Consumption” in order to bypass regulatory prohibitions on the importation and selling of illicit narcotics and NPSs. All medications sold in powder form may be chopped (mixed) with other chemicals, reducing the purity of the dose and causing undesired consequences.

Other types of dissociatives

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How is methoxetamine used?

One of the most noticeable distinctions between ketamine and MXE is the time it takes for its effects to be felt. MXE is thought to be slower acting, but more potent and long-lasting. It can take between 5 and 90 minutes to feel the benefits. People have overdosed as a result of taking extra doses while waiting for the effect to be felt.

MXE is typically snorted, ingested, or injected. The effects are usually felt within 15–45 minutes of taking it orally. The effects of snorting are said to be felt within a few minutes.


Effects of Methoxetamine (MXE)

Any medicine has some danger associated with it. When taking any form of medication, it is critical to use extreme caution.

MXE can have varied effects on different people depending on:

  • the quantity taken.
  • a person’s height, weight, and overall health.
  • whether the individual is accustomed to taking it.
  • Whether or not additional medicines are being taken at the same time.
  • the drug’s strength (which can vary from batch to batch)

In small doses the following effects may occur and may last for up to 7 hours:

  • euphoria
  • pleasant sensory experience
  • dissociation
  • vivid hallucinations
  • introspection
  • anti-depressant
  • empathy

Some adverse methoxetamine effects include:

  • rapid heart rate
  • nausea
  • paranoia
  • vomiting
  • disorientation
  • confusion
  • dizziness
  • anxiety

Higher doses or long-term use of MXE can lead to:

  • cardiovascular problems
  • respiratory damage
  • memory loss
  • panic attacks
  • depression.
  • increased risk of injury
  • speech difficulties

Long-term usage of MXE, like ketamine, has been linked to kidney damage and cystitis.


The consequences of combining pharmaceuticals, whether over-the-counter or prescribed, can be unpredictable and deadly. There is minimal research on the effects of MXE when coupled with other medications. According to anecdotal evidence, combining MXE with alcohol, cannabis, or antidepressants should be avoided.





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