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Etizolam-2, also known as Deschloroetizolam, is a thienotriazolodiazepine compound that is the dechlorinated analog of etizolam. Thienotriazolodiazepines are a class of substances related to benzodiazepines, known for their central nervous system depressant effects. Etizolam-2 has been sold as a designer drug and is chemically similar to etizolam, a thienodiazepine derivative that acts as a benzodiazepine analog. Buy Deschloroclotizolam online | Deschloroetizolam for sale
DCCl is similar in structure to clonazepam (Klonopin), lorazepam (Ativan), and alprazolam (Xanax). It is unclear how potent this drug is, but it is likely to be addictive and potentially dangerous.
What is deschloroclotizolam?
Deschloroclotizolam known as 5-chloro-6-(2-chlorophenyl)-1-methyl-1H-indole-2-carboxylic acid, is a benzodiazepine analog and thienotriazolodiazepine derivative that has emerged as a designer drug, first identified in Sweden in 2021. It belongs to the class of thienodiazepines and is structurally related to benzodiazepines, with a thiophene ring replacing the benzene ring, making it a thienodiazepine.
Deschloroclotizolam is a synthetic thienodiazepine derivative, closely related to other well-known benzodiazepines like diazepam and alprazolam. Unlike its relatives, deschloroclotizolam is not approved for medical use and is primarily encountered in the context of recreational use and scientific research.
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So far, deschloroclotizolam is a powerful anxiolytic and sedative. It’s also been found to be effective in treating panic disorders and seizures. Researchers are still investigating the drug’s full potential, but it looks like deschloroclotizolam could be an important tool in the treatment of a variety of psychiatric disorders.
Chemical Composition and Properties
Deschloroclotizolam, also known as Clotizolam-2, is chemically identified by the IUPAC name 2-chloro-9-methyl-4-phenyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine. It has a molecular weight of 314.8 g/mol and appears as a crystalline solid or powder, soluble in solvents like DMSO and ethanol (Chemical Route) (Cayman Chemical).
What Is The Most Potent Benzodiazepine?
What are the side effects?
The side effects of Deschloroetizolam are the same as the other benzodiazepine drugs that have similar properties. They include
- drowsiness,
- dizziness,
- slow heart rate,
- excitation,
- tachycardia,
- insomnia,
- hallucinations,
- sedation,
- depression,
- low blood pressure,
- and hyperhidrosis.
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Deschloroetizolam for sale
Deschloroetizolam and etizolam are both thienodiazepines, but they differ in their chemical structure. Deschloroetizolam is the dechlorinated analog of etizolam, meaning it lacks the chlorine atom at the 2′ position on the benzene ring. This structural difference makes deschloroetizolam less potent than etizolam, with a duration that is twice as long as its parent compound.
Mechanism of Action
Deschloroclotizolam interacts with the benzodiazepine receptor site on the GABA_A receptor. This interaction enhances the effect of the neurotransmitter GABA, resulting in increased neuronal inhibition. The resultant sedative, anxiolytic, and hypnotic effects are what make deschloroclotizolam both attractive and dangerous (PsychonautWiki).
Usage and Administration
Typically, deschloroclotizolam is consumed orally, often in the form of tablets or capsules. It is primarily used recreationally for its sedative and anxiolytic properties. Users report feelings of relaxation and reduced anxiety, though these effects are often accompanied by drowsiness and impaired coordination (Research chemicals exploring –).
Recreational Use and Effects:
- Deschloroclotizolam exhibits anxiolytic, sedative, hypnotic, muscle relaxant, anticonvulsant, and amnesic effects by acting on GABA receptors
- Users may experience intense sedation, decreased inhibition, amnesia, anxiety suppression, thought deceleration, and analysis suppression
- The compound has a relatively fast onset of action and provides symptomatic relief lasting longer than its parent compound etizolam
Risks and Recommendations:
- Abrupt discontinuation of deschloroclotizolam can be dangerous and potentially life-threatening due to the risk of seizures or other severe outcomes
- Fatal overdose may occur when combined with other depressants like opiates or alcohol, emphasizing the importance of avoiding such combinations
- Harm reduction practices are strongly recommended when using deschloroclotizolam due to its addictive nature and potential for tolerance development.
Differences Between Deschloroclotizolam and Other Benzodiazepines
Deschloroclotizolam, a thienotriazolodiazepine derivative, exhibits distinct characteristics compared to other benzodiazepines. Here are some key differences based on the provided search results:
- Chemical Structure:
- Deschloroclotizolam contains a thiophene ring fused to a diazepine ring, making it a thienotriazolodiazepine
- Unlike traditional benzodiazepines, deschloroclotizolam has a unique structural composition with a thiophene ring replacing the benzene ring
- Pharmacological Effects:
- Deschloroclotizolam produces anxiolytic, sedative, hypnotic, muscle relaxant, anticonvulsant, and amnesic effects by binding to modulatory sites on GABA receptors, similar to benzodiazepines
- The compound has a relatively fast onset of action and provides symptomatic relief lasting longer than its parent compound etizolam
Legal Status
The legal status of deschloroclotizolam varies widely across different countries. In many regions, it is classified as a controlled substance or falls into a legal grey area, making its purchase and use potentially illegal. It’s crucial to check local regulations to understand its legal standing (Research chemicals exploring –).
Potential Effects and Risks
Positive Effects
- Sedation: Users experience profound relaxation.
- Anxiolysis: Significant reduction in anxiety levels.
- Hypnosis: Enhanced ability to fall asleep.
Negative Effects
- Drowsiness: Can impair daily functioning.
- Memory Impairment: Difficulty in forming new memories.
- Coordination Issues: Increases risk of accidents (Research chemicals exploring –) (Chemical Route).
Addiction and Tolerance
Deschloroclotizolam is highly addictive, both physically and psychologically. Tolerance to its effects can develop rapidly, often within a few days of continuous use. Withdrawal symptoms can be severe and potentially life-threatening, including seizures if the drug is abruptly discontinued (PsychonautWiki).
Overdose Risks
Overdosing on deschloroclotizolam, particularly when combined with other depressants like alcohol or opioids, can lead to respiratory depression, coma, or death. Immediate medical intervention is critical in cases of overdose (PsychonautWiki).
FAQs
Is Deschloroclotizolam detectable in drug tests? While not commonly included in standard drug tests, specialized tests can detect its presence (Research chemicals exploring –).
Can Deschloroclotizolam be purchased online? It can sometimes be found on online marketplaces or darknet sites, though legality and safety remain significant concerns (Research chemicals exploring –).
What should I do if I suspect someone is overdosing on Deschloroclotizolam? Seek emergency medical attention immediately. Overdoses require prompt and professional treatment to prevent serious health outcomes (Chemical Route).
Key Takeaways
- Deschloroclotizolam is a powerful thienodiazepine with significant sedative effects.
- Its use is highly addictive and carries a substantial risk of overdose.
- The legal status varies by country, necessitating careful attention to local laws.
- It is not approved for medical use and should be handled with extreme caution.
Understanding the complexities and risks associated with deschloroclotizolam is crucial for those considering its use and for healthcare professionals who may encounter it in clinical settings. Always prioritize safety and legal compliance when dealing with substances of this nature.
References
- PsychonautWiki. Deschloroclotizolam. PsychonautWiki.
- ReseaChem. Deschloroclotizolam. ReseaChem.
- Cayman Chemical. Deschloroclotizolam (CAS 1629324-97-5). Cayman Chemical.
- European Monitoring Centre for Drugs and Drug Addiction. New psychoactive substances: 25 years of early warning and response in Europe. EMCDDA.
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