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How Long Does Flualprazolam Stay in Your Urine? | Flualprazolam half-life

Flualprazolam, a triazolobenzodiazepine, has acquired consideration as a calming drug with comparable unfavorable responses to alprazolam. If you’re wondering how long flualprazolam stays in your urine, it’s essential to consider various factors that can affect its detection time.  Flualprazolam half-life

Flualprazolam, a triazolobenzodiazepine, has a median detection time of 49 hours (range 25-98) in urine


Flualprazolam has become a subject of interest due to its potential as a psychoactive substance [2]. Understanding its detection time in urine is crucial for drug screening purposes or assessing its presence in the body.

Flualprazolam: An Overview

Flualprazolam is a benzodiazepine subordinate that bears similarities to alprazolam, a broadly recommended medicine for tension and frenzy problems. It exhibits sedative, hypnotic, and anxiolytic properties, making it appealing to people seeking recreational or self-medication purposes. However, flualprazolam is not approved for medical use and is classified as a new psychoactive substance [2].


Flualprazolam Details
Street Name Flualp
Chemical Class Triazolobenzodiazepine
Approval Status Not FDA approved
Use Recreational


Flualprazolam has a molecular formula of C17H12ClFN4 and a molecular weight of 326.76 g/mol. Its structure includes a benzene ring fused to a diazepine ring and a triazolo ring, with various attachments enhancing its potency.

Chemical Structure Details
Molecular Formula C17H12ClFN4
Molecular Weight 326.76 g/mol
Key Components Benzene ring, Diazepine ring, Triazolo ring

Detection of Flualprazolam in Urine

Various medication testing methods, for example, immunoassays and corroborative methodologies like gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-mass spectrometry (LC-MS), are utilized to find flualprazolam in urine. These tests can identify and quantify the presence of flualprazolam metabolites in urine samples.

Determining the relative performance of real-time PCR (rtPCR) for the detection of Leptospira borgpetersenii serovar Hardjo in urine from naturally infected cattle, it was found that 60% (25/42) of culture-positive samples were positive by rtPCR, 91% (20/22) of culture-positive samples were rtPCR-positive, 50% (16/32) of FAT-positive samples were rtPCR-positive, 90% (9/10) of samples that were culture-positive but FAT-negative were rtPCR-positive, and 25% (5/20) of samples that were FAT-positive but culture-negative were rtPCR-positive

Flualprazolam vs clonazolam

Assuming you or somebody close has become dependent on etizolam or Xanax, treatment is accessible to assist you with recuperating. Assuming you are being evaluated for work, you might need to inform your manager that you have taken Xanax ahead of time. A test lab will let you know if you have taken it without a solution, taken a medication test, or can decipher the outcomes accurately.


While there’s limited published information on flualprazolam’s pharmacology, DEA studies indicate that it binds to GABA receptors more effectively than diazepam and flumazenil. Online reports describe effects such as sedation and physical impairment, with onset of action within 10-30 minutes and a long duration of action (6-14 hours).

Pharmacological Effects Details
Receptor Binding Greater affinity than diazepam
Onset of Action 10-30 minutes
Duration of Action 6-14 hours
Reported Effects Sedation, physical impairment, potential for coma

Illicit Uses

Flualprazolam is mainly abused for its sedative and hypnotic effects. Online forums compare its effects to those of clonazepam and alprazolam. It is one of the most common benzodiazepine-type novel psychoactive substances (NPS) found in postmortem and DUI cases.

Illicit Use Details
Effects Sedative, hypnotic
Comparisons Clonazepam, alprazolam
Common Cases Postmortem, DUI

User Population

The primary users of flualprazolam are young adults, particularly males, who seek its recreational effects.

User Demographics Details
Main Users Young adults
Gender Predominantly males

Illicit Distribution

Flualprazolam is often sold online as a research chemical and is usually found in pill form, mimicking the appearance of legitimate medications like Xanax™ and Klonopin™. Reports of flualprazolam have increased significantly in recent years.

Distribution Method Details
Purchase Channels Internet
Common Forms Pill form
Increase in Reports Significant rise from 2017 to 2021

Control Status

As of 2020, flualprazolam is controlled under Schedule I of the Controlled Substances Act in the United States and included in Schedule IV of the 1971 Convention on Psychotropic Substances.

Control Status Details
U.S. Schedule Schedule I
International Status Schedule IV

Factors Affecting Detection Time

  1. Dosage: The amount of flualprazolam consumed plays a significant role in its detection time. Higher doses may prolong the substance’s presence in urine.
  2. Frequency of Use: Individuals who frequently use flualprazolam are more likely to have a longer detection window.
  3. Metabolism: Variations in metabolism among individuals can affect the elimination rate of flualprazolam from the body.
  4. Urinary pH: The pH level of urine can impact the excretion of flualprazolam and its metabolites.
  5. Body Mass: Body composition, including weight and fat percentage, can influence the elimination of flualprazolam.

Flualprazolam half-life

Flualprazolam is a benzodiazepine that is known to have a long elimination half-life of its parent compound, alprazolam. The specific half-life of flualprazolam isn’t known; however, it is assessed to be longer than 24 hours. It is essential to take note that an abrupt cessation of benzodiazepines can be hazardous or even perilous for people who are heavy or long-term clients. Subsequently, people who are truly subject to this substance are encouraged to tighten their portions bit by bit over a drawn out period as opposed to halting use unexpectedly. It is likewise encouraged to just utilize flualprazolam for brief timeframes, and in the event that it is utilized as a crisis substitute, to stay away from benzodiazepine withdrawal, to stay away from impulsive redosing, and to limit the regulated portion as much as could be expected.

Detection Time of Flualprazolam in Urine

The detection time of flualprazolam in urine can vary depending on the factors mentioned above. While specific data for flualprazolam is limited, it is essential to note that benzodiazepines, in general, have a relatively long detection window in urine.

Based on available information, flualprazolam may be detectable in urine for up to 5-7 days following the last use, depending on individual factors and testing methods [8].

How Long Do Opiates Stay in Your System?

Factors Affecting Opiate Elimination

The duration of opiate presence in the body can vary significantly depending on several factors, including:

  1. Type of Opiate: Different opiates have varying half-lives and metabolic pathways, influencing their elimination rates.
  2. Dosage and Duration of Use: Higher doses and prolonged use can prolong the detection window.
  3. Individual Metabolism: Factors like age, weight, body fat percentage, and liver and kidney function can impact opiate metabolism and excretion.
  4. Frequency of Use: Regular or chronic opiate use can lead to accumulation in body tissues, resulting in longer detection times.

Detection Methods and Timelines

Opiates can be detected through various testing methods, each with its own detection window. Here’s an overview of common detection methods and their respective timelines:

Urine Testing

Urine tests are among the most common methods for detecting opiate use. The detection window for opiates in urine can vary:

  • Morphine: Up to 3 days after the last dose.
  • Codeine: Up to 3 days after the last dose.
  • Heroin: Up to 3-4 days after the last dose.
  • Oxycodone: Up to 3-4 days after the last dose.
  • Hydrocodone: Up to 3-4 days after the last dose.

Blood Testing

Blood tests can detect the presence of opiates, but they have a relatively short detection window:

  • Morphine: Up to 12 hours after the last dose.
  • Codeine: Up to 24 hours after the last dose.
  • Heroin: Up to 6-12 hours after the last dose.
  • Oxycodone: Up to 24 hours after the last dose.
  • Hydrocodone: Up to 24 hours after the last dose.

Saliva Testing

Saliva tests can detect opiate use for a shorter duration compared to urine tests:

  • Morphine: Up to 4 days after the last dose.
  • Codeine: Up to 1-4 days after the last dose.
  • Heroin: Up to 5 hours after the last dose.
  • Oxycodone: Up to 1-4 days after the last dose.
  • Hydrocodone: Up to 1-4 days after the last dose.

Hair Testing

Hair testing can provide a longer detection window, as opiates can be detected in hair for several months after use:

  • Morphine: Up to 90 days after the last dose.
  • Codeine: Up to 90 days after the last dose.
  • Heroin: Up to 90 days after the last dose.
  • Oxycodone: Up to 90 days after the last dose.
  • Hydrocodone: Up to 90 days after the last dose.

Withdrawal Symptoms and Treatment

As opiates leave the body, individuals may experience withdrawal symptoms, which can range from mild to severe. Common withdrawal symptoms include:

  • Muscle aches and pain
  • Anxiety and irritability
  • Nausea and vomiting
  • Sweating and chills
  • Insomnia and restlessness

Seeking professional help and entering a medically supervised detoxification program is crucial for managing withdrawal symptoms and increasing the chances of successful recovery.


Key Points to Remember

  • Flualprazolam is a potent benzodiazepine not approved for medical use.
  • It has significant sedative and hypnotic effects, with a high potential for abuse.
  • The substance is controlled under strict regulations due to its dangers.

For further information or to report additional data, contact the DEA’s Drug and Chemical Evaluation Section via email at [email protected].


Flualprazolam, a novel psychoactive substance, can be detected in urine using appropriate drug testing methods. The detection time varies depending on various factors, including dosage, frequency of use, metabolism, urinary pH, and body mass. Understanding the approximate detection window of flualprazolam in urine is crucial for drug screening and assessing its presence in the body.



  1. Q: Can flualprazolam be detected in urine after a week of use? A: Depending on individual factors and testing methods, flualprazolam can be detected in urine for up to 5-7 days following the last use.
  2. Q: Are there any home drug testing kits available for flualprazolam? A: While specific home drug testing kits for flualprazolam may not be widely available, specialized laboratories and medical facilities can conduct urine tests to detect its presence.
  3. Q: Can other benzodiazepines cross-react and produce false-positive results in urine tests for flualprazolam? A: Cross-reactivity with other benzodiazepines may occur in urine tests, potentially leading to false-positive results. Confirmatory testing is necessary to differentiate between different benzodiazepines.
  4. Q: How long does flualprazolam stay in other body fluids, such as blood or saliva? A: The detection time of flualprazolam in blood or saliva may differ from urine. Further research and information are needed to provide accurate estimates.
  5. Q: Is flualprazolam legally regulated? A: Flualprazolam is not approved for medical use in most jurisdictions and is considered a controlled or illicit substance. The legal status of flualprazolam may vary depending on regional regulations.