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1-Pentyl-3-(1-naphthoyl)indole (additionally called AM-678 and JWH-018) is a full agonist manufactured cannabinoid first orchestrated by natural scientist John W. Huffman. It picked up notoriety in late 2008 when German scientists discovered it as a compound inside the mainstream engineered medical marijuana mix Spice, which had been sold in various nations around the globe since 2002.

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