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Desmethylmoramide is an opioid analgesic related to dextromoramide . It was synthesized and characterized in the late 1950s but was never marketed.  Desmethylmoramide is a morpholinopyrrolidine and an opioid receptor agonist. It has been used in a variety of scientific studies. Its molecular formula is C24H30N2O2 . Desmethylmoramide is a derivative of the opioid morphine .Buy Desmethylmoramide online from rcchemsupply for safe and effective performance enhancement. Fast and discreet delivery is available.

What is Desmethylmoramide?

Desmethylmoramide, also known by its International Nonproprietary Name (INN), is a synthetic opioid analgesic drug. It is derived from Moramide, a pharmaceutical drug developed in the mid-20th century. Desmethylmoramide acts as a central nervous system depressant and exhibits potent pain-relieving properties. Desmethylmoramide has about three times greater opioid efficacy than morphine but a far shorter duration of action. Nowadays, desmethylmoramide is allowed in several nations.

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History and Background

Desmethylmoramide was first synthesized in the 1950s as a derivative of Moramide. Moramide itself was developed as a potential alternative to morphine, aiming to retain its analgesic effects while reducing the risk of addiction and respiratory depression. However, Desmethylmoramide did not achieve widespread acceptance and eventually fell out of medical use due to safety concerns and the emergence of other opioid medications.

Chemical Structure and Properties

Desmethylmoramide has a complex chemical structure consisting of multiple rings and functional groups. Its molecular formula is C21H26N2O2, and it belongs to the morphinan class of opioids. The compound is a white, crystalline powder that is sparingly soluble in water but more soluble in organic solvents.

 

Synonyms	Desmethylmoramide
IUPAC	4-Morpholin-4-yl-2,2-diphenyl-1-pyrrolidin-1-ylbutan-1-one
Formula	C24H30N2O2
Molecular weight	378.516 g•mol−1
CAS	1767-88-0
Appearance	Powder
Purity	≥ 98%

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Pharmacology and Mechanism of Action

The mechanism of action of Desmethylmoramide is related to its activity as an opioid receptor agonist. As an opioid analgesic, it binds to the mu-opioid receptors in the central nervous system, which results in the inhibition of the release of neurotransmitters such as substance P, dopamine, and acetylcholine. This inhibition leads to a reduction in pain perception, sedation, and respiratory depression . Desmethylmoramide has been shown to have analgesic activity in rodents. However, it is important to note that opioids, in general, can cause side effects such as nausea, vomiting, constipation, dizziness, confusion, sedation, respiratory depression, and addiction. It is recommended to use opioids only under the supervision of a healthcare professional and to follow the prescribed dosage and instructions

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Medical Uses

Desmethylmoramide was initially developed as an analgesic for the management of pain. However, due to safety concerns and the availability of alternative medications, it is no longer commonly used in clinical settings. Its use is restricted to limited cases where other treatment options have proven ineffective or unsuitable.

Side Effects and Risks

There is limited information available on the potential side effects of Desmethylmoramide. As an opioid analgesic, it is related to dextromoramide and morphine. According to a study, little is known about the effects and harm potential of Desmethylmoramide as a new synthetic opioid. It is important to note that opioids, in general, can cause side effects such as nausea, vomiting, constipation, dizziness, confusion, sedation, respiratory depression, and addiction. It is recommended to use opioids only under the supervision of a healthcare professional and to follow the prescribed dosage and instructions

Legal Status of Desmethylmoramide

The legal status of Desmethylmoramide varies across different jurisdictions. In many countries, it is classified as a controlled substance due to its potential for abuse and addiction. The production, distribution, and use of Desmethylmoramide may be regulated by law, requiring appropriate authorization and prescription.

Desmethylmoramide Abuse and Addiction

Although Desmethylmoramide is not commonly encountered in illicit drug markets, its potential for abuse and addiction should not be overlooked. Individuals who misuse Desmethylmoramide may seek its euphoric effects, leading to an increased risk of addiction. It is important to raise awareness about the risks associated with its misuse and promote responsible prescribing practices.

Treatment for Desmethylmoramide Addiction

Treating Desmethylmoramide addiction typically involves a comprehensive approach that combines medical interventions, counseling, and support services. Detoxification, medication-assisted treatment, behavioral therapies, and peer support can play crucial roles in helping individuals overcome addiction and regain control over their lives. Buy Desmethylmoramide online

Comparison with Other Opioids

When comparing Desmethylmoramide with other opioids, it is essential to consider factors such as potency, duration of action, side effect profile, and abuse potential. Each opioid has its unique characteristics and may be more suitable for specific medical conditions or patient populations. Healthcare professionals carefully evaluate these factors to determine the most appropriate opioid therapy for each individual.

Research and Development

Although Desmethylmoramide is no longer widely used, ongoing research and development efforts in the field of opioids continue to explore new compounds with improved safety and efficacy profiles. Researchers aim to develop medications that provide effective pain relief while minimizing the risk of addiction, respiratory depression, and other adverse effects.